There has been a growing problem of wastewater entering the ecosystem without being treated or reused and, at the same time, of the significant loss of freshwater. To improve the way in which water resources are managed, essential processes are the desalination of seawater and the purification of polluted waters. Current extraction and purification approaches to produce water fresh and/or clean water for human, industrial and agricultural uses suffer from limited selectivity and efficiency. Therefore, the development of highly efficient membranes efficiency, to obtain clean water in a controlled way, in less time and with less energy, is a major challenge in this field [1-5]. This project, in accordance with Sustainable Development Goal 6 (SDG 6), aims at the manufacture of new membranes for reverse osmosis reverse osmosis. The membranes will be made by electrospinning polymers (from solution or suspension) or prepolymers and then photo cross-linking the fibers to ensure mechanical and chemical robustness of the membranes produced. The conditions of the above processes will be optimized to obtain the most suitable membranes in terms of morphology, porosity, hydrophilicity, thermal stability and antimicrobial activity. The membranes will be used in reverse osmosis systems treating saline water and water polluted with metals.